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Optimize GIF animations in a lossy way in PHP using free API:

<?php
$url = 'http://server.com/animation.gif';
$level = 15; //Higher = smaller size but worse quality
$data = json_decode(file_get_contents('http://api.rest7.com/v1/gif_lossy.php?url=' . $url . '&level=' . $level));

if (@$data->success !== 1)
{
    die('Failed');
}
$anim = file_get_contents($data->file);
file_put_contents('optimized.gif', $anim);